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Grapes are not only delicious but also known for their aphrodisiac properties. They are rich in antioxidants and nutrients, similar to grape seed extract (GSE), which is packed with beneficial compounds like proanthocyanidin.
Grape seed extract is derived from grape seeds and is commonly used to address various health issues caused by free radicals, including obesity, diabetes, and cancer.
The high antioxidant content in GSE, particularly proanthocyanidin, helps prevent diseases and protects against oxidative stress, tissue damage, and inflammation.
- Reduces Blood Pressure
Numerous studies have examined the impact of GSE on high blood pressure. A review of 16 studies involving 810 individuals with high blood pressure or at high risk revealed that daily consumption of 100-2000 mg of GSE significantly reduced both systolic and diastolic blood pressure by an average of 5.08 mmHg and 2.8 mmHg, respectively. The most significant improvements were observed in people under 50 years old with obesity or metabolic disorders, with a lower dosage (100-800 mg daily) over 8-16 weeks proving more effective than higher doses. - Improves Blood Flow
Research indicates that GSE can enhance blood flow. In an 8-week study involving 17 healthy postmenopausal women, consuming 400 mg of GSE daily led to blood-thinning effects, potentially lowering the risk of blood clots. Another study on healthy young women found that a single dose of 400 mg of GSE reduced leg swelling and edema by 70% after prolonged sitting. - Reduces Oxidative Damage
Elevated levels of bad cholesterol (LDL) are a known risk factor for heart disease, with oxidation of LDL playing a central role in the development of atherosclerosis. GSE supplementation has been shown to reduce LDL oxidation in both animal and human studies. For instance, when 8 healthy individuals consumed 300 mg of GSE after a high-fat meal, the oxidation of fat in the blood was significantly inhibited. In another study with 61 adults, daily intake of 400 mg of GSE led to a 13.9% reduction in oxidized LDL levels. - Enhances Collagen Levels and Bone Strength
Flavonoids, abundant in GSE, contribute to collagen synthesis and bone formation, thereby improving bone density and strength. Animal studies have demonstrated that adding GSE to a diet with varying calcium levels can increase bone density, mineral content, and strength. Additionally, GSE has shown potential in reducing pain and joint damage in osteoarthritis by increasing collagen levels and decreasing cartilage loss. - Supports Brain Health with Age
The antioxidant and anti-inflammatory properties of GSE may help delay or reduce the onset of neurodegenerative diseases such as Alzheimer’s. Studies have shown that components of GSE, like gallic acid, can inhibit the formation of harmful proteins in the brain associated with Alzheimer’s. In animal studies, GSE has been found to prevent memory loss, improve cognitive function, and reduce brain lesions. A 12-week study on 11 healthy adults also found that daily intake of 150 mg of GSE improved attention, language, and memory. - Improves Kidney Function
Kidneys are particularly vulnerable to oxidative damage, which can often be irreversible. Animal studies suggest that GSE can reduce kidney damage and improve function by lowering oxidative stress and inflammation. In a study involving 23 individuals with chronic kidney failure, daily intake of 2 grams of GSE for 6 months led to a 3% reduction in urinary protein and a 9% improvement in kidney filtration. - Inhibits Infection Growth
GSE exhibits antibacterial and antifungal properties. Studies have shown that GSE can inhibit the growth of common foodborne bacteria, including Campylobacter and E. coli, which often cause severe food poisoning. Additionally, GSE has been found to inhibit strains of antibiotic-resistant Staphylococcus aureus and is traditionally used to treat candida overgrowth. - Reduces Cancer Risk
While cancer is a complex disease with various causes, DNA damage is a central factor. The intake of antioxidants like those found in GSE is associated with a reduced risk of various cancers. GSE’s antioxidant activity has shown potential in inhibiting the growth of breast, lung, gastric, liver, prostate, and pancreatic cancer cells in laboratory studies. - Protects the Liver
The liver plays a crucial role in detoxifying harmful substances. GSE has demonstrated protective effects on the liver in test-tube studies by reducing inflammation, recycling antioxidants, and protecting against damage from toxins. In one study, 15 individuals with non-alcoholic fatty liver disease showed a 46% reduction in liver enzyme ALT levels after 3 months of GSE supplementation, compared to minimal changes in a group taking vitamin C. - Enhances Wound Healing and Skin Appearance
Animal studies suggest that GSE can aid in wound healing. In a study with 35 adults who underwent minor surgery, those who applied a 2% GSE cream experienced complete wound healing in 8 days, compared to 14 days for the placebo group. GSE’s high proanthocyanidin content may trigger skin growth and improve skin elasticity, appearance, and nutrient content. - Promotes Skin Health
Grape seed is rich in vitamins C and E, as well as antioxidants, which contribute to healthier skin and reduce signs of aging. GSE’s proanthocyanidins and resveratrol offer protection against sunburn and UV damage. Studies have shown that GSE can reduce the appearance of wrinkles and improve skin texture, with a small trial reporting an 88% improvement in skin texture after 6 weeks of using a GSE-containing product. Grape seed oil is also known for its moisturizing properties, making it an effective treatment for hydrating and smoothing the skin.
